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037 _5BiblioBoard
245 0 0 _aAging and Health
_bA Systems Biology Perspective /
_cAnatoliy I. Yashin, S. Michal Jazwinski.
020 _a9783318027303
029 1 _ahttps://library.biblioboard.com/ext/api/media/08d0513c-f9f8-46b3-be57-53e19d095343/assets/thumbnail.jpg
040 _aScCtBLL
_cScCtBLL
506 0 _aAccess copy available to the general public.
_fUnrestricted
_2star
700 1 _aYashin, Anatoliy I.
_eeditor.
700 1 _aJazwinski, S. Michal
_eeditor.
264 1 _bKarger,
300 _a1 online resource (1 p.)
520 _aAging is a major risk factor for chronic diseases, which in turn can provide information about the aging of a biological system. This publication serves as an introduction to systems biology and its application to biological aging. Key pathways and processes that impinge on aging are reviewed, and how they contribute to health and disease during aging is discussed. The evolution of this situation is analyzed, and the consequences for the study of genetic effects on aging are presented. Epigenetic programming of aging, as a continuation of development, creates an interface between the genome and the environment. New research into the gut microbiome describes how this interface may operate in practice with marked consequences for a variety of disorders. This analysis is bolstered by a view of the aging organism as a whole, with conclusions about the mechanisms underlying resilience of the organism to change, and is expanded with a discussion of circadian rhythms in aging.
588 0 _aDescription based on print version record.
590 _aKU Select 2018: STEM Backlist Books
650 7 _aMedical / Geriatrics
_2bisacsh
650 0 _aMedicine
655 0 _aElectronic books.
758 _iIs found in:
_aKnowledge Unlatched
_1https://openresearchlibrary.org/module/2774bc74-146a-484f-a7ba-ab1d6a09bbfb
856 4 0 _uhttps://openresearchlibrary.org/content/08d0513c-f9f8-46b3-be57-53e19d095343
_zView this content on Open Research Library.
_70
999 _c33211
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